Publications
2024
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Dion M Z & Artzi N. "Polypeptide agonists of innate immune sensors." Nature Biomedical Engineering, 8, 495-496 (2024). https://doi.org/10.1038/s41551-024-01212-8
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Anchordoquy T, Artzi N, Balyasnikova I V, Barenholz Y, La-Beck N M, Brenner J S, Chan W C W, Decuzzi P, Exner A A, Gabizon A, Godin B, Lai S K, Lammers T, Mitchell M J, Moghimi M, Muzykantov V R, Peer D, Nguyen J, Popovtzer R, Ricco M, Serkova N J, Singh R, Schroeder A, Schwendeman A A, Straehla J P, Teesalu T, Tilden S, and Simberg D. "Mechanism and Barriers in Nanomedicine: Progress in the Field and Future Directions." ACS Nano, 2024, 18(22), 13983-13999. https://doi.org/10.1021/acsnano.4c00182
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Younis N, Puigmal N, Kurdi A E, Badaoui A, Zhang D, Morales C, Saad A, Cruz D, Rahy N A, Daccache A, Huerta T, Deban C, Halawi A, Choi J, Dosta P, Lian C, Artzi N#, Azzi J R#. "Microneedle-Mediated Delivery of Immunomodulators Restores Immune Privilege in Hair Follicles and Reverses Immune-Mediated Alopecia." Advanced Materials, 2024. https://doi.org/10.1002/adma.202312088. #Corresponding authors. PDF.
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Munoz T G, Dahis D, Edelman E, and Artzi N. "Sprayable Hydrogel Sealant for Gastrointestinal Wound Shielding." Advanced Materials, 2024. https://doi.org/10.1002/adma.202311798. PDF.
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Kudruk, S, Forsyth C M, Dion, M Z, Hedlund Orbeck J K, Luo J, Klein R S, Kim A H, Heimberger A B, Mirkin C A, Stegh A H, and Artzi N. “Multimodal neuro-nanotechnology: Challenging the existing paradigm in glioblastoma therapy.” PNAS, 2024. https://doi.org/10.1073/pnas.2306973121. PDF.
2023
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Liz-Marzan LM, Artzi N, Bals S, Buriak JM, Chan W CW, Chen X, Hersam MC, Kim I-D, Millstone JE, Mulvaney P, Parak WJ, Rogach A, and Schaak RE. "Celebrating a Nobel Prize to the Discovery of Quantum Dots, an Essential Milestone in Nanoscience." American Chemical Society Nano, 2023. https://doi.org/10.1021/acsnano.3c09671.
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Chan, W CW, Artzi N, Chen C, Chen X, Ho D, Hu T, Kataoka K, Liz-Marzan LM, Oklu R, and Parak WJ. "Noble Nanomedicine: Celebrating Groundbreaking mRNA Vaccine Innovations." American Chemical Society Nano, 2023. https://doi.org/10.1021/acsnano.3c09781.
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Dahis D, Dion M, Cryer AM, Dosta P, Gilboa T, Alonso M, Lewandowski M, Puigmal N, Munoz Taboada G, Azhari H, Ahmad R, Walt DR, and Artzi N. "Monitoring Melanoma Responses to STING Agonism and Focused Ultrasound Thermal Ablation Using Microneedles and Ultrasensitive Single Molecule Arrays." Advanced Functional Materials, 2023. https://doi.org/10.1002/adfm.202301659. PDF.
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Dosta P, Cryer AM, Dion MZ, Shiraishi T, Langston SP, Lok D, Wang J, Harrison S, Hatten T, Ganno ML, Appleman VA, Munoz G, Puigmal N, Ferber S, Kalash S, Prado M, Rodriguez AL, Kamoun WS, Abu-Yousif AO, and Artzi N. "Investigation of the enhanced antitumor potency of STING agonist after conjugation to polymer nanoparticles." Nature Nanotechnology, 2023. https://doi.org/10.1038/s41565-023-01447-7. PDF.
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Freeman FE, Dosta P, Shanley LC, Tamez NR, Riojas CJ, Javelly OR, Mahon D, Kelly J, and Artzi N. "Localized Nanoparticle-Mediated Delivery of miR-29b Normalizes the Dysregulation of Bone Homeostasis Caused by Osteosarcoma", Advanced Materials, 2023. DOI: 10.1002/adma.202207877. PDF.
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Mayoral-Pena K Gonzalez Pena O I, Artzi N, and de Donato M. "Identification of biomarkers for breast cancer early diagnosis based on the molecular classification using machine learning algorithms on transcriptomic data and factorial designs for analysis." 2023. https://www.researchsquare.com/article/rs-2877610/v1.
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Puigmal N, Ramos V, Artzi N, and Borros S. "Poly(β-amino ester)s-Based Delivery Systems for Targeted Transdermal Vaccination." Pharmaceutics, 2023. https://doi.org/10.3390/pharmaceutics15041262.
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Dion MZ and Artzi N. 2023. "Engineering Immunity to Disease Using Nanotechnology." Nanochemistry: Synthesis, Characterization and Applications, pp. 229-278, CRC Press.
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Buriak MJ, Akinwande D, Artzi N, Brinker JC, Burrows C, Chan WCW, Chen C, Chen X, Chhowalla M, Chi L, Chueh W, Crudden CM, Di Carlo D, Glotzer SC, Hersam MC, Ho D, Hu TY, Huang J, Javey A, Kamat P V, Kim II-D, Kotov NA, LL TR, Lee YH, Luis YL, Liz-Marzan L, Mulvaney P, Narang P, Nordlander P, Oklu R, Parak WJ, Rogach AL, Salanne M, Samori P, Schaak R E, Scanze K S, Sekitani T, Skrabalak S, Sood AK, Votes I K, Wang S, Wang S, Wee A T S, and Ye J. "Best Practices for Using AI When Writing Scientific Manuscripts: Caution, Care, and Consideration: Creative Science Depends on It." ACS Nano, 2023. https://doi.org/10.1021/acsnano.3c01544.
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Dahis D, Azagury DM, Obeid F, Dion M, Cryer A, Alonso Riquelme M, Dosta P, Abraham A W, Gavish M, and Artzi N. "Focused Ultrasound enhances brain delivery of sorafenib nanoparticles." Advanced Nanobiomed Research, 2023. https://doi.org/10.1002/anbr.202200142. PDF.
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Dosta P, Puigmal N, Cryer A M, Rodríguez AL, Scott E, Weissleder R, Mille MA, and Artzi N. "Polymeric microneedle-based platform enables simultaneous delivery of cancer immunomodulatory drugs and detection of biomarkers in the skin." Theranostics, 2023. DOI: 10.7150/thno.73966. PDF.
2022
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Muñoz Taboada G, Dosta P, Edelman ER, Artzi N. "Sprayable Hydrogel for Instant Sealing of Vascular Anastomosis", Advanced Materials, 2022. https://doi.org/10.1002/adma.202203087. PDF.
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Freeman FE, Burdis R, Mahon OR, Kelly DJ, and Artzi N. "A Spheroid Model of Early and Late-Stage Osteosarcoma Mimicking the Divergent Relationship between Tumor Elimination and Bone Regeneration", Advanced Healthcare Materials, 2022. https://doi.org/10.1002/adhm.202101296.
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Ahmadi S, Sukprasert P, Vegesna R, Sinha S, Schischlik F, Arzi N, Khuller S, Schaffer AA, and Ruppin E. "The landscape of receptor-mediated precision cancer combination therapy via a single-cell perspective", Nature Communications, 2022. https://doi.org/10.1038/s41467-022-29154-2.
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Cryer AM and Artzi N. "Chapter Five - Engineered devices for tumor microenvironment immune modulation", Science Direct, 2022. https://doi.org/10.1016/B978-0-323-90949-5.00005-X.
2021
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Dahis D, Farti N, Romano R, Artzi N, and Azhari H. "Ultrasonic Thermal Monitoring of the Brain Using Golay Coded Excitations – Feasibility Study", IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2021. DOI: 10.1109/TUFFC.2021.3132094.
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Puigmal N, Dosta P, Solhjou Z, Yatim K, Ramírez C, Choi JY, Haddad J, Cosme AP, Azzi J, and Artzi N. "Microneedle-Based Local Delivery of CCL22 and IL-2 Enriches Treg Homing to the Skin Allograft and Enables Temporal Monitoring of Immunotherapy Efficacy." Advanced Functional Materials, 2021. DOI: 10.1002/adfm.202100128. PDF.
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Dosta P, Cryer A, Prado M, Dion M, Ferber S, Kalash S, and Artzi N. "Delivery of STING Agonist Using Polypeptide-Modified Dendrimer Nanoparticles in the Treatment of Melanoma", Advanced NanoBiomed Research, 2021. DOI: 10.1002/anbr.202100006. PDF.
2020
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Dosta P, Ferber S, Zhang Y, Wang K., Ros A, Uth N, Levinson Y, Abraham E, and Artzi N. "Scale-up Manufacturing of Gelatin-based Microcarriers for Cell Therapy" Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 2020. PDF.
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Artzi N. “Materializing Personalized Medicine“, Advanced Materials, 2020. PDF.
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Muñoz Taboada G, Yang K, Pereira M, Liu S, Hu Y, Karp JM, Artzi N, and Lee Y. "Overcoming the translational barriers of tissue adhesives. Nature Review Materials 5, 310-329, 2020. PDF.
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Ahmadi S, Sukprasert P, Artzi N, Khuller S, Schaffer A, and Ruppin E. “The Landscape of Precision Cancer Combination Therapy: A Single-Cell Perspective” BioRxiv, 2020, ,PDF.
2019
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Zhang Y, Dosta P, Conde J, Oliva N, Wang M, and Artzi N. “Prolonged Local In Vivo Delivery of Stimuli-Responsive Nanogels That Rapidly Release Doxorubicin in TripleNegative Breast Cancer Cells.” Advanced Healthcare Materials, 2019. PDF.
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Ferber S, Gonzalez RJ, Cryer AM, von Andrian UH, and Artzi N. “Immunology-guided biomaterial design as mucosal cancer vaccine.” Advanced Materials, 2019. PDF.
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Strecker SE, Unterman S, Charles LF, Pivovarchick D, Maye PF, Edelman ER, and Artzi N. “Osterix-mCherry Expression Allows For Early Bone Detection In A Calvarial Defect Model.” Advanced BioSystems, 2019. PDF
2017
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Abraham E, Gadish O, Franses J, Chitalia V, Artzi N, and Edelman E. "Matrix-Embedded Endothelial Cells Attain a Progenitor-Like Phenotype." Advanced Biosystems, 2017. PDF
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Zhu G, Falahat F, Wang K, Mailloux A, Artzi N, and Mulé J. "Tumor-Associated Tertiary Lymphoid Structures: Gene-Expression Profiling and Their Bioengineering." Frontiers in Immunology, 2017. PDF
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Oliva N, Conde J, Wang K, andArtzi N. "Designing Hydrogels for On-Demand Therapy." Accounts of Chemical Research, 2017. PDF
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Unterman S, Charles LF, Strecker SE, Kramarenko D, Pivovarchik D, Edelman ER, and Artzi N. "Hydrogel Nanocomposites with Independently Tunable Rheology and Mechanics." ACS Nano, 2017. PDF
2016
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Gilam A, Conde J, Weissglas-Volkov D, Oliva N, Friedman E, Artzi N, and Shomron N. "Local microRNA delivery targets Palladin and prevents metastatic breast cancer." Nature Communications, 2016. PDF
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Conde J, Oliva N, Zhang Y, and Artzi N. "Local triple-combination therapy results in tumour regression and prevents recurrence in a colon cancer model." Nature Materials, 2016. PDF Featured in Science Translational Medicine
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Conde J, Shomron N, and Artzi N. "Biomaterials for Metastasis: Bridging the Gap between Basic and Translational Research." Advanced Healthcare Materials (VIP paper), 2016. PDF
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Conde J, Oliva N., and Artzi N. "Revisiting the ‘one material fits all’ rule for cancer nanotherapy." Trends in Biotechnology, 2016. PDF
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Song HS, Kwon, OS, Kim JH, Conde J, and Artzi N. "3D Hydrogel Scaffold Doped With 2D Graphene Materials For Biosensors And Bioelectronics." Biosensors and Bioelectronics, 2016. PDF
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Kwon OS, Song HS, Conde J, Kim H, Artzi N, and Kim JH. "Dual-Color Emissive Upconversion Nanocapsules for Differential Cancer Bioimaging in vivo." ACS Nano, 2016. PDF
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Faucher KM, Artzi N, Beck M, Beckerman R, Moodie G, Albergo T, Conroy S, Dale A, Corbeil S, Martakos P, and Edelman ER. "Tracking of Drug Release and Material Fate for Naturally Derived Omega-3 Fatty Acid Biomaterials." Annals of Biomedical Engineering, 2016. PDF
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Conde J, Oliva N, Atilano M, Song HS, and Artzi N. "Self-assembled RNA-triple-helix hydrogel scaffold for microRNA modulation in the tumour microenvironment." Nature Materials, 15, 353-363, 2016. PDF Featured in Science Translational Medicine
2015
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Artzi N, Tzafriri AR, Faucher KM, Moodie G, Albergo T, Conroy S, Corbeil S, Martakos P, Virmani R, and Edelman ER. "Sustained efficacy and arterial drug retention by a fast drug eluting cross-linked fatty acid coronary stent coating." Annals of Biomedical Engineering, 2015. PDF
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Unterman S*, Freiman A, Beckerman M, Abraham E, Stanley JRL, Levy E, Artzi N*, and Edelman E. "Tuning of collagen scaffold properties modulates embedded endothelial cell regulatory phenotype in repair of vascular injuries in vivo." Advanced Healthcare Materials, 2015. PDF
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Conde J, Arnold C, Tian F, and Artzi N. "RNAi nanomaterials targeting immune cells as an anti-tumor therapy: the missing link in cancer treatment?" Materials Today, 2015. PDF
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Bao C, Conde J, Curtin J, Artzi N, Tian F, and Cui D. "Bioresponsive antisense DNA gold nanobeacons as a hybrid in vivo theranostics platform for the inhibition of cancer cells and metastasis." Scientific Reports, 5, 12297, 2015. PDF
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Conde J, Bao C, Tan Y, Cui D, Edelman ER, Azevedo HS, Byrne HJ, Artzi N and Tian F. "Dual targeted immunotherapy via in vivo delivery of biohybrid RNAi-peptide nanoparticles to tumour-associated macrophages and cancer cells." Advanced Functional Materials, 2015. PDF
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Conde J and Artzi N. "The next generation of smart gold nanobeacons: nanotheranostics is ready for prime-time." Nanomedicine (Lond.), 10, 1535-1538, 2015. PDF
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Oliva N, Unterman S, Zhang Y, Conde J, Song HS, and Artzi N. "Personalizing biomaterials for precision nanomedicine in light of local tissue microenvironment." Advanced Healthcare Materials, 2015. PDF
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Conde J, Oliva N, and Artzi N. “Implantable hydrogel embedded dark-gold nanoswitch as a theranostics probe to sense and overcome cancer multidrug resistance.” PNAS, 112, 1278-1287, 2015. PDF Featured in Nature Reviews Drug Discovery PDF
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Conde J and Artzi N. "Are RNAi and miRNA therapeutics truly dead?" Trends in Biotechnology, 33, 141-144, 2015. PDF
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Tzur-Balter A, Shatsberg Z, Beckerman M, Segal E, and Artzi N. “Mechanism of Erosion of Nanostructured Porous Si Drug Carriers in Neoplastic Tissues.” Nature Communications, 6, 2015. PDF
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Oliva N, Carcole M, Beckerman R, Hayward A, Stanley B, Parry N, Edelman ER, and Artzi N. "Regulation of dendrimer:dextran material performance by the altered tissue microenvironment in inflammation and neoplasia." Sci Trans Med, 7, 272ra11, 2015. Featured in Science Translational Medicine. PDF
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Conde J, Edelman ER, and Artzi N. "Target-responsive DNA/RNA nanomaterials for microRNA sensing and inhibition: The jack-of-all-trades in cancer nanotheranostics?" Adv Drug Deliv Rev., 81, 169-183, 2015. PDF
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French A, Bravery C, Smith J, Chandra A, Archibald P, Gold JD, Artzi N, Kim HW, Barker RW, Meissner A, Wu JC, Knowles JC, Williams D, García-Cardeña G, Sipp D, Oh S, Loring JF, Rao MS, Reeve B, Wall I, Carr, AJ Bure K, Stacey G, Karp JM, Snyder EY, and Brindley DA. "Enabling Consistency in Pluripotent Stem Cell-Derived Products for Research and Development and Clinical Applications Through Material Standards." Stem Cells Transl Med. 2015. PDF
2014 and prior
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N. Segovia, M. Pont, N. Oliva, V. Ramos, S. Borrós, N. Artzi. "Hydrogel Doped with Nanoparticles for Local Sustained Release of siRNA in Breast Cancer". Adv Healthc Mater., 2014, 4, 271-280. PDF
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N. Artzi & E. Edelman. “Aldehyde-Amine Chemistry Enables Tissue Adhesive Materials to Respond to Physiologic Variation and Pathologic States”, Israel Journal of Chemistry, 53 (9-10), 748-755, 2013. PDF
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N. Oliva, S. Shitreet, E. Abraham, B. Stanley, E.R. Edelman, N. Artzi. "Natural tissue microenvironmental conditions modulate adhesive material performance". Langmuir, 28(43), 15402-9, 2012. PDF
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N. Artzi, A. Zeiger, F. Boehning, A. Bon Ramos, K. Van Vliet, E. R. Edelman. “Tuning adhesion failure strength for tissue-specific applications”. Acta Biomater, 7(1), 67-74, 2011. PDF
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N. Artzi, N. Oliva, C. Puron, S. Shitreet, S. Artzi, A. bon Ramos, A. Groothuis, G. Sahagian, E.R. Edelman. "In vivo and in vitro tracking of erosion in biodegradable materials using non-invasive fluorescence imaging". Nature Materials, 10(9), 704-9, 2011. PDF
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N. Artzi, T. Shazly, A. Baker, A. Bon, and E. Edelman “Aldehyde-Amine Chemistry Enables Modulated Biosealants with Tissue-Specific Adhesion”, Advanced Materials, 21(32- 33), 3399-3403, 2009. Featured in Nature Medicine. PDF
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N. Artzi, T. Shazly, C. Crespo, and E. Edelman “Characterization of Star Adhesive Sealant Based on PEG: Dextran Hydrogels”, Macromolecular Bioscience, 9(8), 754-765, 2009. PDF
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T. Shazly, N. Artzi, F. Boehning, and E. Edelman “Viscoelastic Adhesive Mechanics of Aldehyde-Mediated Soft Tissue Sealants”, Biomaterials, 29(35), 4584-4591, 2008. PDF
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N. Artzi, B. B. Khatua, Narkis and A. Siegmann, “Studies on nylon-6/EVOH/clay ternary composites”, Polymer Composites, 27(1), 15-23, 2006. PDF
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N. Artzi, “Why Nano-Composites Are In? A Glimpse Into Polymer Based Nanocomposites”, Reviews in Chemical Engineering, 21(5), 307-345, 2005.
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D. Aleperstein, N. Artzi,A. Siegmann, and M. Narkis, “Experimental and Computational Investigation of EVOH/clay Nanocomposites”, Journal of Applied Polymer Science, 97(5), 2060-2066, 2005. PDF
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N. Artzi, M. Narkis, and A. Siegmann, “EVOH/clay Nanocomposite Systems: Processing, Structure, Property Relationships”, Annual Technical Conference - Society of Plastics Engineers, 63rd, 1461-1465, 2005.
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N. Artzi, M. Narkis, and A. Siegmann, “Review of Melt-Processed EVOH/organoclay Nanocomposites”, J. Polym. Sci., Part B:Polymer Physics, 43(15), 1931- 1943, 2005. PDF
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N. Artzi, A. Tzur, M. Narkis, and A. Siegmann, “The Effect of Extrusion Processing Conditions on EVOH/clay Nanocomposites at Low Organo-Clay Contents”, Polymer Composites, 26(3), 343-351, 2005. PDF
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N. Artzi, B.B. Khatua, R. Tchoudakov, M. Narkis, A, Berner, A. Siegmann, J.M. Lagaron, “Physical and Chemical Interactions in Melt Mixed Nylon-6/EVOH Blends”, J. Macromol. Sci., Part B: Phys., B43(3), 605-624, 2004.
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N. Artzi, M. Narkis, and A. Siegmann, “EVOH/clay Nanocomposites Produced by Dynamic Melt Mixing”, Polym. Eng. Sci., 44(6), 1019-1026, 2004. PDF
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N. Artzi, Y. Nir, M. Narkis, and A. Siegmann, “The Effect of Maleated Compatibilizers on the Structure and Properties of EVOH/Clay Nanocomposites”, Polymer Composites, 24, 627-639, 2003. PDF
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N. Artzi, Y. Nir, M. Narkis, and A. Siegmann, “Melt Blending of EVOH/Clay nanocomposites: Effect of Clay Type and Processing Conditions”, J. Polym. Sci., Part B:Polymer Physics, 40, 1741-1753, 2002. PDF
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N. Artzi, Y. Nir, D. Wang, M. Narkis, and A. Siegmann, “EVOH/Clay Nanocomposites Produced by Melt Processing”, Polymer Composites, 22, 710-720, 2001. PDF